The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this …

MYC has two paralogues: MYCL and MYCN. The initially held view was that MYC is ubiquitously involved in human cancers (both haematological and solid), whereas L-MYC is associated with small …

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Nov 14, 2025 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphomaand High-Grade B-Cell Lymphoma Double …

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Feb 19, 2025 · This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials.

Aug 10, 2022 · As an oncogenic driver, MYC amplifies global transcription by driving pause release and the early transcription, especially of highly expressed genes. It stimulates replication by facilitating …

The myc family includes four transcription factors, c-myc, N-myc, L-myc, and S-myc, involved in the control of cell growth, differentiation, and apoptosis (69).

A family of genes that makes proteins involved in many cell functions, including cell growth, cell maturation, and cell death. Genetic changes in the DNA sequence of the MYC genes have been …

Because of its high prevalence of deregulation and its causal role in cancer formation, maintenance and progression, targeting MYC is theoretically an attractive strategy for treating cancer.