The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and the ...
This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...
Why Do Large B-Cell Lymphoma Patients With High Tumor Mutation Burden Relapse on CAR T-Cell Therapy?
Researchers explored this question at ASH and shared data suggesting genomic instability in tumors with high TMB likely ...
Single-cell sequencing provides unprecedented detail into cell-to-cell variability, uncovering key biological mechanisms in ...
Scientists have identified a potential new treatment strategy for Alzheimer’s disease using a combination of two existing cancer drugs. The research suggests that targeting multiple types of brain ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
Salidroside (2- (4-Hydroxyphenyl) ethyl β-D-glucopyranoside, SAL) is a bioactive compound present in Rhodiola rosea L., exhibiting diverse pharmacological properties such as anti-inflammatory and anti ...
The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jcim.5c00731. Comparison of model complexity between scGANSL and other ...
Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...
Abstract: Single-cell RNA sequencing (scRNA-seq), a powerful technique for investigating the transcriptome of individual cells, enables the discovery of heterogeneous cell populations, rare cell types ...
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