DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new wave of research is forcing a rethink, showing that the three-dimensional ...

We grow up hearing that our skin, hair, body shape, and even how we age are all written into our DNA. And yes—genetics leave ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings ...

Scientists have discovered that Madagascar’s iconic Pinocchio chameleon is actually a distinct species now named Calumma ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the ...

A study used DNA origami to form 2D fishnet structures on silicon, testing growth conditions and advancing DNA-assisted ...