Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

Mapping transcription factor (TF) binding sites across the genome is key to understanding how cells control gene expression, yet pinpointing their footprints across the genome—especially in single ...

A new treatment may be in sight for stroke patients after scientists successfully reprogrammed immune cells to replace damaged brain cells and restore brain function after stroke-like injury. Every ...

Topological heterogeneity of genomic and immunologic effects from combination immunotherapy treatment in the neoadjuvant setting for renal cell carcinoma (RCC). This is an ASCO Meeting Abstract from ...

Membrane fusion and budding mediate fundamental biological processes like intracellular trafficking, exocytosis, and endocytosis. For many decades, fusion has been thought to open a nanometer-range ...

CD19-targeted CAR T-cell therapy shows a 65% response rate in Richter transformation, with median progression-free survival of 8 months and overall survival of 14.4 months. Early response and age are ...