In an ongoing clinical trial, researchers are testing whether just one dose of a new gene therapy that might effectively cure human immunodeficiency virus (HIV) infections is safe in humans. According ...
In a provocative first step toward an elusive end to a devastating disease that has claimed 40 million lives, three patients have received CRISPR gene-editing therapies in an effort to eradicate HIV ...
The first trial to show that vaccination could confer HIV protection was the RV144 HIV vaccine trial. This trial reported an efficacy of 31%. A key element of the RV144 trial was gp120, generated in ...
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Tests in animal models by researchers at the Lewis Katz School of Medicine at Temple University, and at the University of Nebraska Medical Center (UNMC) have shown how gene editing two targets, HIV-1 ...
In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to snip the AIDS-causing virus out of his cells. For an hour, he was hooked up to an IV ...
Excision BioTherapeutics has so far released positive safety data from the first 3 participants living with HIV-1, with no evidence of vector shedding in sexual organ tissue. A cure for HIV-1 becomes ...
Scientists at Excision BioTherapeutics are running a human clinical trial for a new CRISPR-based drug called EBT-101 which targets human immunodeficiency virus (HIV) infections. There are many tests ...
Johannes holds an MSci in Neuroscience from King’s College London, where he worked on projects involving Alzheimer’s disease and Fragile X syndrome. Johannes holds an MSci in Neuroscience from King’s ...
Dr. Michael Emerman, a professor in the Human Biology and Basic Sciences Divisions of Fred Hutch, has been hunting the secrets of HIV replication for decades. “There are nearly 40 million people ...
The concept of CRISPR gene-editing is still quite young. Although the discovery of CRISPRs themselves—repeating DNA sequences present in single-celled organisms, such as bacteria—can be traced back to ...
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